CAS 107-14-2 chloroacetonitrile insoluble in water chloroacetonitrile liquid
Alias: Chloromethane cyanide, Chloromethyl cyanide
Appearance: Colorless transparent liquid
Chemical formula: C2H2ClN
Particular weight: 75.497
CAS: 107-14-2
EINECS: 203-467-0
Melting point: 38 ℃
Boiling point: 124℃—-126 ℃
Water soluble: insoluble
Density: 1.193 g/cm³
Flash point: 47.8 ℃
Security description
S45;S61
Hazard Symbols: T
Hazard description: R23/24/25;R51/53
Refractive index: 1.422 (20℃)
Saturated vapor pressure: 1.064kPa (20℃)
Solubility: insoluble in water, soluble in hydrocarbons and alcohols
Toxicological data
- Chronic toxicity
Mouse transdermal TDLo: 4800mg/kg/2W
- Mutagenicity
Mutation of microorganism Salmonella typhimurium: 20mg/L
DNA damage in human lymphocytes: 15 μmol/L
Non-mammalian multiplexed micronucleus assay: 1250 μg/L
Oral DNA synthesis in rats: 115mg/kg
Sister chromatid exchange in hamster ovary: 79100 μmol/L
- Has a strong irritating and tearing effect. Toxic by inhalation, oral intake or in contact with skin
- Subacute and Chronic Toxicity
Rat inhalation, 60.2mg/m3, 6h each time, a total of 20 times, no signs of poisoning, necropsy showed mild renal congestion.
- Carcinogenicity
IARC Carcinogenicity Review: G3, Insufficient Evidence for Carcinogenicity in Humans and Animals
Application
Mainly used as analytical reagents, fumigants, pesticides, solvents, organic synthesis intermediates
Protective measures
Respiratory protection: Self-priming filter respirators (full face masks) should be worn when exposure to its vapors is possible. In emergency rescue or evacuation, it is recommended to wear isolation respirator.
Eye Protection: Respiratory protection has been covered.
Body Protection: Wear polyethylene protective clothing.
Hand Protection: Wear rubber gloves.
Others: Smoking, eating and drinking are prohibited at the workplace. After work, wash thoroughly. Work clothes are not allowed to be brought to non-work places. Store poison-contaminated clothes separately and wash them for later use.
